Tandem chain extension–Mannich reaction: an approach to β-proline derivatives
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چکیده
منابع مشابه
β-Phenylproline: the high β-turn forming propensity of proline combined with an aromatic side chain.
The conformational propensities of the proline analogue bearing a phenyl substituent attached to the β carbon, in either a cis or a trans configuration relative to the carbonyl group, have been investigated. The behaviour of cis- and trans(βPh)Pro has been compared with that of proline in homochiral and heterochiral dipeptide sequences. NMR and IR studies as well as X-ray diffraction analysis p...
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ژورنال
عنوان ژورنال: Tetrahedron
سال: 2012
ISSN: 0040-4020
DOI: 10.1016/j.tet.2012.07.039